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Merck

UBE2V1

ubiquitin-conjugating enzyme E2 variant 1

Synonyms:
CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Species:
Human UBE2V1 (7335), Mouse Ube2v1 (66589), Rat Ube2v1 (296390), Zebrafish ube2v1 (641324), chicken UBE2V1 (100538349), dog UBE2V1 (477262), dog UBE2V1 (100538347), cow UBE2V1 (617771)
UniProtKB ID:
Q13404, E1P629, Q13403, Q13532, Q5TGE0, Q5TGE3, Q96H34, Q9GZT0
Gene ID:
  • Human(7335) Summary: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Apr 2012]
  • Mouse(66589) ubiquitin-conjugating enzyme E2 variant 1
  • Rat(296390) ubiquitin-conjugating enzyme E2 variant 1
  • Zebrafish(641324) ubiquitin-conjugating enzyme E2 variant 1
  • chicken(100538349) ubiquitin-conjugating enzyme E2 variant 1
  • dog(477262) ubiquitin-conjugating enzyme E2 variant 1
  • dog(100538347) ubiquitin-conjugating enzyme E2 variant 1
  • cow(617771) ubiquitin-conjugating enzyme E2 variant 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2109147
Anti-UBE2V1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, pig, rat, zebrafish
Application
western blot