TP53
tumor protein p53
Synonyms:
BCC7, LFS1, P53, TRP53
Species:
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...More
UniProtKB ID:
Gene ID:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Zebrafish(30590) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- cow(281542) tumor protein p53
- sheep(443421) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-p53 Binding Protein 1 (Ab-1) Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
human, mouse
Application
Anti-p53 (pantropic) Antibody, clone DO-1, clone DO-1, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-p53 (Ab-1) (Pantropic) Mouse mAb (PAb421), lyophilized, clone PAb421, Calbiochem®,
Species Reactivity
human, monkey, mouse, rabbit, rat
Application
Anti-acetyl-p53 Antibody (Lys373, Lys382), serum, Upstate®,
Species Reactivity
vertebrates
Application
western blot
Anti-p53 (Ab-3) (Mutant) Mouse mAb (PAb240), lyophilized, clone PAb240, Calbiochem®,
Species Reactivity
bovine, chicken, hamster, human, mouse, rat
Application
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
p53 (1-342) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
p53 (1-363) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
p53 (1-81), wild type, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Species
esiRNA
Product Number
Description
Species