TIMP2
TIMP metallopeptidase inhibitor 2
Synonyms:
CSC-21K, DDC8
Species:
Human TIMP2 (7077), Mouse Timp2 (21858), Rat Timp2 (29543), chicken TIMP2 (374178), dog TIMP2 (403633), Horse TIMP2 (100034134), domestic cat TIMP2 (101083125), domestic guinea pig Timp2 (100135629), naked mole-rat Timp2 (101707659), Domestic Rabbit TIMP2 (100008689) ...More
UniProtKB ID:
Gene ID:
- Human(7077) Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
- Mouse(21858) tissue inhibitor of metalloproteinase 2
- Rat(29543) TIMP metallopeptidase inhibitor 2
- chicken(374178) TIMP metallopeptidase inhibitor 2
- dog(403633) TIMP metallopeptidase inhibitor 2
- Horse(100034134) TIMP metallopeptidase inhibitor 2
- domestic cat(101083125) TIMP metallopeptidase inhibitor 2
- domestic guinea pig(100135629) tissue inhibitor of metalloproteinase 2
- naked mole-rat(101707659) TIMP metallopeptidase inhibitor 2
- Domestic Rabbit(100008689) TIMP metallopeptidase inhibitor 2
- cow(282093) TIMP metallopeptidase inhibitor 2
- sheep(100217406) TIMP metallopeptidase inhibitor 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TIMP-2 Antibody, clone 2TMP05, clone 2TMP05, Chemicon®, from mouse,
Species Reactivity
bovine, guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-TIMP-2 Antibody, clone 67-4H11, clone 67-4H11, Chemicon®, from mouse,
Species Reactivity
bovine, goat, guinea pig, human, mouse, rabbit, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TIMP2 Antibody, clone 8R5Q2, Rabbit Monoclonal, ,
Species Reactivity
african green monkey, human, mouse, rat
Application
western blot
Proteins
Product Number
Description
Species
TIMP-2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human