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Merck

TARBP2

TAR (HIV-1) RNA binding protein 2

Synonyms:
LOQS, TRBP, TRBP1, TRBP2
Species:
UniProtKB ID:
Gene ID:
  • Human(6895) Summary: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
  • Mouse(21357) TAR (HIV) RNA binding protein 2
  • Rat(363006) TAR (HIV-1) RNA binding protein 2
  • cow(514674) TAR (HIV-1) RNA binding protein 2
  • sheep(101102467) TAR (HIV-1) RNA binding protein 2
  • naked mole-rat(101701286) TAR (HIV-1) RNA binding protein 2
  • domestic guinea pig(100731044) TAR (HIV-1) RNA binding protein 2
  • Zebrafish(336141) TAR (HIV) RNA binding protein 2
  • domestic cat(101087415) TAR (HIV-1) RNA binding protein 2
  • dog(100684088) TAR (HIV-1) RNA binding protein 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TARBP2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse TARBP2,
Species
mouse
MISSION® esiRNA, targeting human TARBP2,
Species
human