STAT4
signal transducer and activator of transcription 4
Synonyms:
SLEB11
Species:
Human STAT4 (6775), Mouse Stat4 (20849), Rat Stat4 (367264), Zebrafish stat4 (368519), chicken STAT4 (768406), dog STAT4 (478845), domestic cat STAT4 (101080650), Horse STAT4 (100054693), domestic guinea pig Stat4 (100726892), Domestic Rabbit STAT4 (100344146) ...More
UniProtKB ID:
Gene ID:
- Human(6775) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
- Mouse(20849) signal transducer and activator of transcription 4
- Rat(367264) signal transducer and activator of transcription 4
- Zebrafish(368519) signal transducer and activator of transcription 4
- chicken(768406) signal transducer and activator of transcription 4
- dog(478845) signal transducer and activator of transcription 4
- domestic cat(101080650) signal transducer and activator of transcription 4
- Horse(100054693) signal transducer and activator of transcription 4
- domestic guinea pig(100726892) signal transducer and activator of transcription 4
- Domestic Rabbit(100344146) signal transducer and activator of transcription 4
- naked mole-rat(101718558) signal transducer and activator of transcription 4
- cow(515988) signal transducer and activator of transcription 4
- sheep(101117562) signal transducer and activator of transcription 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-STAT4 Antibody, clone 10H10O9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-STAT4-Y693 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species