SRP72
signal recognition particle 72kDa
Synonyms:
BMFF
Species:
Human SRP72 (6731), Mouse Srp72 (66661), Rat Srp72 (498351), fruit fly Srp72 (42439), Horse SRP72 (100053755), domestic cat SRP72 (101084282), dog SRP72 (403944), chicken SRP72 (422626), Zebrafish srp72 (327335), cow SRP72 (509430) ...More
UniProtKB ID:
Gene ID:
- Human(6731) Summary: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
- Mouse(66661) signal recognition particle 72
- Rat(498351) signal recognition particle 72
- fruit fly(42439) Signal recognition particle protein 72
- Horse(100053755) signal recognition particle 72kDa
- domestic cat(101084282) signal recognition particle 72kDa
- dog(403944) signal recognition particle 72kDa
- chicken(422626) signal recognition particle 72kDa
- Zebrafish(327335) signal recognition particle 72
- cow(509430) signal recognition particle 72kDa
- sheep(101109358) signal recognition particle 72kDa
- domestic guinea pig(100730467) signal recognition particle 72kDa
- naked mole-rat(101722196) signal recognition particle 72kDa
- Domestic Rabbit(100348339) signal recognition particle 72kDa
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