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Merck

SLC6A5

solute carrier family 6 (neurotransmitter transporter), member 5

Synonyms:
GLYT-2, GLYT2, HKPX3, NET1
Species:
UniProtKB ID:
Gene ID:
  • Human(9152) Summary: This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. [provided by RefSeq, Oct 2009]
  • Mouse(104245) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • Rat(171148) solute carrier family 6 (neurotransmitter transporter), member 5
  • Zebrafish(494450) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • domestic cat(101085314) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • chicken(422974) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • dog(612095) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • cow(528050) solute carrier family 6 (neurotransmitter transporter), member 5
  • sheep(101120368) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • naked mole-rat(101725677) solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • domestic guinea pig(100725884) solute carrier family 6 (neurotransmitter transporter, glycine), member 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Norepinephrine Transporter Antibody, ascites fluid, Chemicon®,
Species Reactivity
human, monkey
Application
immunohistochemistry
Anti-Norepinephrine Transporter Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC6A5,
Species
human
MISSION® esiRNA, targeting mouse Slc6a5,
Species
mouse