SKP1
S-phase kinase-associated protein 1
Synonyms:
EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
Species:
Human SKP1 (6500), Rat Skp1 (287280), Thale Cress SKP1 (843928), Zebrafish skp1 (393716), chicken SKP1 (416319), domestic cat SKP1 (101099017), dog SKP1 (474682), cow SKP1 (615427), Goat SKP1 (100861021), sheep SKP1 (100240716) ...More
UniProtKB ID:
Gene ID:
- Human(6500) Summary: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]
- Rat(287280) S-phase kinase-associated protein 1
- Thale Cress(843928) S-phase kinase-associated protein 1
- Zebrafish(393716) S-phase kinase-associated protein 1
- chicken(416319) S-phase kinase-associated protein 1
- domestic cat(101099017) S-phase kinase-associated protein 1
- dog(474682) S-phase kinase-associated protein 1
- cow(615427) S-phase kinase-associated protein 1
- Goat(100861021) S-phase kinase-associated protein 1
- sheep(100240716) S-phase kinase-associated protein 1
- domestic guinea pig(100135616) S-phase kinase-associated protein 1A
- naked mole-rat(101704606) S-phase kinase-associated protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SKP1A Mouse mAb (1H8), liquid, clone 1H8, Calbiochem®,
Species Reactivity
human
Application
Anti-SKP1 Antibody, clone 3F3.1, clone 3F3.1, from mouse,
Species Reactivity
human, mouse
Application
immunocytochemistry
western blot
western blot
Anti-SKP1 Antibody, clone 10G5X5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Proteins
Product Number
Description
Species
SCF-Fbw7 Protein Complex, Active, 10 µg, Active complex of four (4) full length, recombinant human enzymes: Fbw7, Skp1, Cul1 & Rbx1. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.,
Species
human
SCF-Skp2 Protein Complex, Active, 10 µg, Active complex of five (5) full length, recombinant human enzymes: Skp1, Skp2, Cul1, Rbx1 & Cks1. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.,
Species
human
esiRNA
Product Number
Description
Species