SIRT6
sirtuin 6
Synonyms:
SIR2L6
Species:
Human SIRT6 (51548), Mouse Sirt6 (50721), Rat Sirt6 (299638), fruit fly Sirt6 (41254), Zebrafish sirt6 (415161), chicken SIRT6 (428332), domestic cat SIRT6 (101100540), dog SIRT6 (485045), cow SIRT6 (535416), sheep SIRT6 (101113327) ...More
UniProtKB ID:
Gene ID:
- Human(51548) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
- Mouse(50721) sirtuin 6
- Rat(299638) sirtuin 6
- fruit fly(41254) CG6284 gene product from transcript CG6284-RB
- Zebrafish(415161) sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
- chicken(428332) sirtuin 6
- domestic cat(101100540) sirtuin 6
- dog(485045) sirtuin 6
- cow(535416) sirtuin 6
- sheep(101113327) sirtuin 6
- naked mole-rat(101706114) sirtuin 6
- domestic guinea pig(100734667) sirtuin 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SIRT6 Antibody, clone 1D0L6, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot