SETD2
SET domain containing 2
Synonyms:
HBP231, HIF-1, HIP-1, HYPB, KMT3A, SET2, p231HBP
Species:
Human SETD2 (29072), Mouse Setd2 (235626), Rat Setd2 (316013), Zebrafish setd2 (794199), Horse SETD2 (100064888), domestic cat SETD2 (101085029), dog SETD2 (476643), chicken SETD2 (420404), cow SETD2 (539860), naked mole-rat Setd2 (101719404)
UniProtKB ID:
Gene ID:
- Human(29072) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
- Mouse(235626) SET domain containing 2
- Rat(316013) SET domain containing 2
- Zebrafish(794199) SET domain containing 2
- Horse(100064888) SET domain containing 2
- domestic cat(101085029) SET domain containing 2
- dog(476643) SET domain containing 2
- chicken(420404) SET domain containing 2
- cow(539860) SET domain containing 2
- naked mole-rat(101719404) SET domain containing 2
- domestic guinea pig(100719166) SET domain containing 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SETD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9956, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry