RRM2B
ribonucleotide reductase M2 B (TP53 inducible)
Synonyms:
MTDPS8A, MTDPS8B, P53R2
Species:
Human RRM2B (50484), Mouse Rrm2b (382985), Rat Rrm2b (299976), cow RRM2B (528960), sheep RRM2B (101123639), naked mole-rat Rrm2b (101718446), domestic guinea pig Rrm2b (100715485), Zebrafish rrm2b (368909), chicken RRM2B (420253), Horse RRM2B (100062030) ...More
UniProtKB ID:
Gene ID:
- Human(50484) Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
- Mouse(382985) ribonucleotide reductase M2 B (TP53 inducible)
- Rat(299976) ribonucleotide reductase M2 B (TP53 inducible)
- cow(528960) ribonucleotide reductase M2 B (TP53 inducible)
- sheep(101123639) ribonucleotide reductase M2 B (TP53 inducible)
- naked mole-rat(101718446) ribonucleotide reductase M2 B (TP53 inducible)
- domestic guinea pig(100715485) ribonucleotide reductase M2 B (TP53 inducible)
- Zebrafish(368909) ribonucleotide reductase M2 b
- chicken(420253) ribonucleotide reductase M2 B (TP53 inducible)
- Horse(100062030) ribonucleotide reductase M2 B (TP53 inducible)
- domestic cat(101099777) ribonucleotide reductase M2 B (TP53 inducible)
- dog(481988) ribonucleotide reductase M2 B (TP53 inducible)
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