RFC1
replication factor C (activator 1) 1, 145kDa
Synonyms:
A1, MHCBFB, PO-GA, RECC1, RFC, RFC140
Species:
Human RFC1 (5981), Mouse Rfc1 (19687), Rat Rfc1 (89809), Thale Cress RFC1 (832261), Horse RFC1 (100064382), domestic cat RFC1 (101094345), dog RFC1 (479112), chicken RFC1 (422788), Zebrafish rfc1 (100037336), domestic guinea pig Rfc1 (100733981) ...More
UniProtKB ID:
Gene ID:
- Human(5981) Summary: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
- Mouse(19687) replication factor C (activator 1) 1
- Rat(89809) replication factor C (activator 1) 1
- Thale Cress(832261) replication factor C1
- Horse(100064382) replication factor C (activator 1) 1, 145kDa
- domestic cat(101094345) replication factor C (activator 1) 1, 145kDa
- dog(479112) replication factor C (activator 1) 1, 145kDa
- chicken(422788) replication factor C (activator 1) 1, 145kDa
- Zebrafish(100037336) replication factor C (activator 1) 1
- domestic guinea pig(100733981) replication factor C (activator 1) 1, 145kDa
- naked mole-rat(101697246) replication factor C (activator 1) 1, 145kDa
- cow(514842) replication factor C (activator 1) 1, 145kDa
- sheep(101109450) replication factor C (activator 1) 1, 145kDa
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