RET
ret proto-oncogene
Synonyms:
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Species:
Human RET (5979), Mouse Ret (19713), Rat Ret (24716), fruit fly ret (44319), fruit fly Ret (43875), Horse RET (100033966), domestic cat RET (101101086), dog RET (403494), chicken RET (396107), Zebrafish ret (30512) ...More
UniProtKB ID:
Gene ID:
- Human(5979) Summary: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
- Mouse(19713) ret proto-oncogene
- Rat(24716) ret proto-oncogene
- fruit fly(44319) reticulated
- fruit fly(43875) Ret oncogene
- Horse(100033966) ret proto-oncogene
- domestic cat(101101086) ret proto-oncogene
- dog(403494) ret proto-oncogene
- chicken(396107) ret proto-oncogene
- Zebrafish(30512) ret proto-oncogene receptor tyrosine kinase
- domestic guinea pig(100733392) ret proto-oncogene
- Domestic Rabbit(100340710) ret proto-oncogene
- naked mole-rat(101717565) ret proto-oncogene
- cow(515924) ret proto-oncogene
- sheep(101119787) ret proto-oncogene
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-c-Ret Antibody, clone 6F3.1, clone 6F3.1, from mouse,
Species Reactivity
human, rat
Application
western blot
Anti-RET Antibody, clone 2K12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Ret Antibody, clone 3U8T6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
Ret (V804M) Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804M mutation. For use in Kinase Assays.,
Species
human
Ret Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658-end, for use in Kinase Assays.,
Species
human
Ret (V804L) Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804L mutation. For use in Kinase Assays.,
Species
human