PTPN14
protein tyrosine phosphatase, non-receptor type 14
Synonyms:
PEZ, PTP36
Species:
Human PTPN14 (5784), Mouse Ptpn14 (19250), Rat Ptpn14 (305064), chicken PTPN14 (421360), domestic cat PTPN14 (101097202), Horse PTPN14 (100050251), dog PTPN14 (490293), cow PTPN14 (518798), sheep PTPN14 (101112408), domestic guinea pig Ptpn14 (100731586)
UniProtKB ID:
Gene ID:
- Human(5784) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]
- Mouse(19250) protein tyrosine phosphatase, non-receptor type 14
- Rat(305064) protein tyrosine phosphatase, non-receptor type 14
- chicken(421360) protein tyrosine phosphatase, non-receptor type 14
- domestic cat(101097202) protein tyrosine phosphatase, non-receptor type 14
- Horse(100050251) protein tyrosine phosphatase, non-receptor type 14
- dog(490293) protein tyrosine phosphatase, non-receptor type 14
- cow(518798) protein tyrosine phosphatase, non-receptor type 14
- sheep(101112408) protein tyrosine phosphatase, non-receptor type 14
- domestic guinea pig(100731586) protein tyrosine phosphatase, non-receptor type 14
- naked mole-rat(101720803) protein tyrosine phosphatase, non-receptor type 14
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