PPAT
phosphoribosyl pyrophosphate amidotransferase
Synonyms:
ATASE, GPAT, PRAT
Species:
Human PPAT (5471), Mouse Ppat (231327), Rat Ppat (117544), cow PPAT (509652), sheep PPAT (101109095), domestic guinea pig Ppat (100730194), naked mole-rat Ppat (101720775), Domestic Rabbit PPAT (100348590), Zebrafish ppat (572027), chicken PPAT (422743) ...More
UniProtKB ID:
Gene ID:
- Human(5471) Summary: The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]
- Mouse(231327) phosphoribosyl pyrophosphate amidotransferase
- Rat(117544) phosphoribosyl pyrophosphate amidotransferase
- cow(509652) phosphoribosyl pyrophosphate amidotransferase
- sheep(101109095) phosphoribosyl pyrophosphate amidotransferase
- domestic guinea pig(100730194) phosphoribosyl pyrophosphate amidotransferase
- naked mole-rat(101720775) phosphoribosyl pyrophosphate amidotransferase
- Domestic Rabbit(100348590) phosphoribosyl pyrophosphate amidotransferase
- Zebrafish(572027) phosphoribosyl pyrophosphate amidotransferase
- chicken(422743) phosphoribosyl pyrophosphate amidotransferase
- domestic cat(101084957) phosphoribosyl pyrophosphate amidotransferase
- Horse(100053805) phosphoribosyl pyrophosphate amidotransferase
- dog(611407) phosphoribosyl pyrophosphate amidotransferase
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Small Molecule - Inhibitor
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