PARP1
poly (ADP-ribose) polymerase 1
Synonyms:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Species:
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), Zebrafish parp1 (560788), chicken PARP1 (396199), dog PARP1 (490385), domestic cat PARP1 (101081434), Horse PARP1 (100058523), cow PARP1 (286764) ...More
UniProtKB ID:
Gene ID:
- Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- Mouse(11545) poly (ADP-ribose) polymerase family, member 1
- Rat(25591) poly (ADP-ribose) polymerase 1
- Thale Cress(817690) poly [ADP-ribose] polymerase 2
- Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
- chicken(396199) poly (ADP-ribose) polymerase 1
- dog(490385) poly (ADP-ribose) polymerase 1
- domestic cat(101081434) poly (ADP-ribose) polymerase 1
- Horse(100058523) poly (ADP-ribose) polymerase 1
- cow(286764) poly (ADP-ribose) polymerase 1
- domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
- naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
- sheep(100135697) poly (ADP-ribose) polymerase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Poly ADP-ribose Antibody, clone 10H, clone 10H, from mouse,
Species Reactivity
human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti- Cleaved PARP1 p25 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti- PARP1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-PARP (214/215) cleavage site Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, human, mouse, rat
Application
immunocytochemistry
western blot
western blot
Anti-PARP Poly ADP-ribose Polymerase-1 Antibody, serum, Chemicon®,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species