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PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

Synonyms:
PAKalpha
Species:
UniProtKB ID:
Gene ID:
  • Human(5058) Summary: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • Mouse(18479) p21 protein (Cdc42/Rac)-activated kinase 1
  • Rat(29431) p21 protein (Cdc42/Rac)-activated kinase 1
  • Zebrafish(373103) p21/Cdc42/Rac1-activated kinase 1
  • domestic cat(101087171) p21 protein (Cdc42/Rac)-activated kinase 1
  • cow(533729) p21 protein (Cdc42/Rac)-activated kinase 1
  • dog(607885) p21 protein (Cdc42/Rac)-activated kinase 1
  • chicken(419083) p21 protein (Cdc42/Rac)-activated kinase 1
  • domestic guinea pig(100714662) p21 protein (Cdc42/Rac)-activated kinase 1
  • naked mole-rat(101713465) p21 protein (Cdc42/Rac)-activated kinase 1
  • sheep(101111756) p21 protein (Cdc42/Rac)-activated kinase 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PAK-1 Antibody, clone 1H5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunohistochemistry

western blot
Anti-PAK1 Antibody, clone 6R3M5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Anti-phospho-PAK1 (Ser199/Ser204) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Phospho-PAK1/2/3-S144/S141/S139 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
PAK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pak1,
Species
mouse
MISSION® esiRNA, targeting human PAK1,
Species
human