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Merck

P2RY1

purinergic receptor P2Y, G-protein coupled, 1

Synonyms:
P2Y1
Species:
Human P2RY1 (5028), Mouse P2ry1 (18441), Rat P2ry1 (25265), chicken P2RY1 (396275), dog P2RY1 (449621), domestic cat P2RY1 (101090795), cow P2RY1 (281963), sheep P2RY1 (101114407), Domestic Rabbit P2RY1 (100353792), domestic guinea pig P2ry1 (100135592)
UniProtKB ID:
P47900
Gene ID:
  • Human(5028) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
  • Mouse(18441) purinergic receptor P2Y, G-protein coupled 1
  • Rat(25265) purinergic receptor P2Y, G-protein coupled, 1
  • chicken(396275) purinergic receptor P2Y, G-protein coupled, 1
  • dog(449621) purinergic receptor P2Y, G-protein coupled, 1
  • domestic cat(101090795) purinergic receptor P2Y, G-protein coupled, 1
  • cow(281963) purinergic receptor P2Y, G-protein coupled, 1
  • sheep(101114407) purinergic receptor P2Y, G-protein coupled, 1
  • Domestic Rabbit(100353792) purinergic receptor P2Y, G-protein coupled, 1
  • domestic guinea pig(100135592) purinergic receptor P2Y, G-protein coupled 1

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Small Molecule - Agonist

Product Number
Description
Species
01905
Adenosine 5′-diphosphate, ≥95% (HPLC),
Species
human
U4125
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
M3808
MRS 2179 ammonium salt hydrate, ≥98% (HPLC),
Species
human
A5285
Adenosine 5′-diphosphate monopotassium salt dihydrate, bacterial, ≥95%, powder,
Species
human
A2754
Adenosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC),
Species
human
01905
Adenosine 5′-diphosphate, ≥95% (HPLC),
Species
human
N8652
NF 023 hydrate, ≥98% (HPLC), solid,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
AB9263
Anti-P2Y1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
SAB2109077
Anti-P2RY1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
S2671
Suramin sodium salt, ≥98% (TLC),
Species
human

esiRNA

Product Number
Description
Species
EHU033811
MISSION® esiRNA, targeting human P2RY1,
Species
human
EMU017741
MISSION® esiRNA, targeting mouse P2ry1,
Species
mouse