P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
P2X1
Human P2RX1 (5023), Mouse P2rx1 (18436), Rat P2rx1 (25505), Zebrafish p2rx1 (387296), chicken P2RX1 (395190), cow P2RX1 (514898), Horse P2RX1 (100060689), domestic cat P2RX1 (101091060), dog P2RX1 (491223), domestic guinea pig P2rx1 (100727772) ...More
- Human(5023) Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
- Mouse(18436) purinergic receptor P2X, ligand-gated ion channel, 1
- Rat(25505) purinergic receptor P2X, ligand-gated ion channel, 1
- Zebrafish(387296) purinergic receptor P2X, ligand-gated ion channel, 1
- chicken(395190) purinergic receptor P2X, ligand-gated ion channel, 1
- cow(514898) purinergic receptor P2X, ligand-gated ion channel, 1
- Horse(100060689) purinergic receptor P2X, ligand-gated ion channel, 1
- domestic cat(101091060) purinergic receptor P2X, ligand-gated ion channel, 1
- dog(491223) purinergic receptor P2X, ligand-gated ion channel, 1
- domestic guinea pig(100727772) purinergic receptor P2X, ligand-gated ion channel, 1
- Domestic Rabbit(100350587) purinergic receptor P2X, ligand-gated ion channel, 1
- naked mole-rat(101722936) purinergic receptor P2X, ligand-gated ion channel, 1
- sheep(101101902) purinergic receptor P2X, ligand-gated ion channel, 1
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