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Merck

P2RX1

purinergic receptor P2X, ligand-gated ion channel, 1

Synonyms:
P2X1
Species:
UniProtKB ID:
Gene ID:
  • Human(5023) Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
  • Mouse(18436) purinergic receptor P2X, ligand-gated ion channel, 1
  • Rat(25505) purinergic receptor P2X, ligand-gated ion channel, 1
  • Zebrafish(387296) purinergic receptor P2X, ligand-gated ion channel, 1
  • chicken(395190) purinergic receptor P2X, ligand-gated ion channel, 1
  • cow(514898) purinergic receptor P2X, ligand-gated ion channel, 1
  • Horse(100060689) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic cat(101091060) purinergic receptor P2X, ligand-gated ion channel, 1
  • dog(491223) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic guinea pig(100727772) purinergic receptor P2X, ligand-gated ion channel, 1
  • Domestic Rabbit(100350587) purinergic receptor P2X, ligand-gated ion channel, 1
  • naked mole-rat(101722936) purinergic receptor P2X, ligand-gated ion channel, 1
  • sheep(101101902) purinergic receptor P2X, ligand-gated ion channel, 1

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Small Molecule - Agonist

Product Number
Description
Species
α,β-Methyleneadenosine 5′-triphosphate lithium salt, ≥93% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Reactive Blue 4, Dye content 35 %,
Species
rat
NF 023 hydrate, ≥98% (HPLC), solid,
Species
human
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-P2Rx1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Suramin sodium salt, ≥98% (TLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human P2RX1,
Species
human
MISSION® esiRNA, targeting mouse P2rx1,
Species
mouse