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Merck

ORAI1

ORAI calcium release-activated calcium modulator 1

Synonyms:
CRACM1, ORAT1, TMEM142A
Species:
UniProtKB ID:
Gene ID:
  • Human(84876) Summary: The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
  • Mouse(109305) ORAI calcium release-activated calcium modulator 1
  • Rat(304496) ORAI calcium release-activated calcium modulator 1
  • chicken(416845) ORAI calcium release-activated calcium modulator 1
  • dog(486261) ORAI calcium release-activated calcium modulator 1
  • cow(517688) ORAI calcium release-activated calcium modulator 1
  • domestic cat(101096922) ORAI calcium release-activated calcium modulator 1
  • domestic guinea pig(100725803) ORAI calcium release-activated calcium modulator 1
  • naked mole-rat(101699660) ORAI calcium release-activated calcium modulator 1
  • sheep(101102013) ORAI calcium release-activated calcium modulator 1

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ORAI1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, horse, human, pig, rabbit, rat, yeast
Application
western blot
Anti-Orai1 Antibody, Intracellular, Chemicon®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-STIM1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Tyrphostin A9, solid,
Species
mouse, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ORAI1,
Species
human