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Merck

NTRK2

neurotrophic tyrosine kinase, receptor, type 2

Synonyms:
GP145-TrkB, TRKB, trk-B
Species:
Human NTRK2 (4915), Mouse Ntrk2 (18212), Rat Ntrk2 (25054), sheep NTRK2 (101116015), Domestic Rabbit NTRK2 (100352548), naked mole-rat Ntrk2 (101720037), domestic guinea pig Ntrk2 (100723565), chicken NTRK2 (396157), cow NTRK2 (505824), Horse NTRK2 (100061700) ...More
UniProtKB ID:
Q16620, B1ANZ4, B4DFV9, Q16675, Q59GJ1, Q8WXJ5, Q8WXJ6, Q8WXJ7
Gene ID:
  • Human(4915) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18212) neurotrophic tyrosine kinase, receptor, type 2
  • Rat(25054) neurotrophic tyrosine kinase, receptor, type 2
  • sheep(101116015) neurotrophic tyrosine kinase, receptor, type 2
  • Domestic Rabbit(100352548) neurotrophic tyrosine kinase, receptor, type 2
  • naked mole-rat(101720037) neurotrophic tyrosine kinase, receptor, type 2
  • domestic guinea pig(100723565) neurotrophic tyrosine kinase, receptor, type 2
  • chicken(396157) neurotrophic tyrosine kinase, receptor, type 2
  • cow(505824) neurotrophic tyrosine kinase, receptor, type 2
  • Horse(100061700) neurotrophic tyrosine kinase, receptor, type 2
  • domestic cat(101101347) neurotrophic tyrosine kinase, receptor, type 2
  • dog(484147) neurotrophic tyrosine kinase, receptor, type 2

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Antibodies

Product Number
Description
Species Reactivity
Application
ZRB1495
Anti-phospho-TrkB (Tyr816) Antibody, clone 2C21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human, mouse, rat, sheep
Application
affinity binding assay
immunocytochemistry
inhibition assay
western blot
AB5372
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB, serum, Chemicon®,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
AB9872
Anti-TrkB Antibody, serum, Chemicon®,
Species Reactivity
mouse, rat
Application
immunohistochemistry
ZRB2714
Anti-TrkB Antibody, clone 3E18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
ELISA
affinity binding assay
immunocytochemistry
HPA074873
Anti-NTRK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
SRP6473
NTRK2/TRKB human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
14-507-M
TrkB Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, human TrkB, amino acids 455-end, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
EHU903421
MISSION® esiRNA, targeting human NTRK2,
Species
human
EMNC009391
MISSION® esiRNA, targeting mouse Ntrk2,
Species
mouse
EMU090371
MISSION® esiRNA, targeting mouse Ntrk2,
Species
mouse