NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
Synonyms:
CNF, NPHN, nephrin
Species:
Human NPHS1 (4868), Mouse Nphs1 (54631), Rat Nphs1 (64563), sheep NPHS1 (101115895), naked mole-rat Nphs1 (101705086), Domestic Rabbit NPHS1 (100354996), domestic guinea pig Nphs1 (100713185), Zebrafish nphs1 (692352), domestic cat NPHS1 (101101018), dog NPHS1 (484571)
UniProtKB ID:
Gene ID:
- Human(4868) Summary: This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
- Mouse(54631) nephrosis 1, nephrin
- Rat(64563) nephrosis 1, congenital, Finnish type (nephrin)
- sheep(101115895) nephrosis 1, congenital, Finnish type (nephrin)
- naked mole-rat(101705086) nephrosis 1, congenital, Finnish type (nephrin)
- Domestic Rabbit(100354996) nephrosis 1, congenital, Finnish type (nephrin)
- domestic guinea pig(100713185) nephrosis 1, congenital, Finnish type (nephrin)
- Zebrafish(692352) nephrosis 1, congenital, Finnish type (nephrin)
- domestic cat(101101018) nephrosis 1, congenital, Finnish type (nephrin)
- dog(484571) nephrosis 1, congenital, Finnish type (nephrin)
- cow(519706) nephrosis 1, congenital, Finnish type (nephrin)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Nephrin Antibody, clone 3B6.1, clone 3B6.1, from mouse,
Species Reactivity
human
Application
western blot
Anti-Nephrin Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Nephrin Antibody, clone 1D16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot