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Merck

MXI1

MAX interactor 1, dimerization protein

Synonyms:
MAD2, MXD2, MXI, bHLHc11
Species:
UniProtKB ID:
Gene ID:
  • Human(4601) Summary: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]
  • Mouse(17859) Max interacting protein 1
  • Rat(25701) MAX interactor 1
  • Zebrafish(30485) max interacting protein
  • dog(609946) MAX interactor 1
  • chicken(423888) MAX interactor 1
  • domestic cat(101092646) MAX interactor 1
  • cow(614509) MAX interactor 1
  • domestic guinea pig(100733154) MAX interactor 1, dimerization protein
  • naked mole-rat(101697683) MAX interactor 1, dimerization protein
  • sheep(101118067) MAX interactor 1, dimerization protein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MXI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mxi1,
Species
mouse
MISSION® esiRNA, targeting human MXI1,
Species
human