MUC1
mucin 1, cell surface associated
Synonyms:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Species:
Human MUC1 (4582), Mouse Muc1 (17829), Rat Muc1 (24571), chicken MUC1 (426412), cow MUC1 (281333), domestic cat MUC1 (100294522), domestic cat MUC1 (101093832), dog MUC1 (448784), sheep MUC1 (101106133), sheep MUC1 (100294589) ...More
UniProtKB ID:
Gene ID:
- Human(4582) Summary: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
- Mouse(17829) mucin 1, transmembrane
- Rat(24571) mucin 1, cell surface associated
- chicken(426412) mucin 1, cell surface associated
- cow(281333) mucin 1, cell surface associated
- domestic cat(100294522) mucin 1, cell surface associated
- domestic cat(101093832) mucin 1, cell surface associated
- dog(448784) mucin 1, cell surface associated
- sheep(101106133) mucin 1, cell surface associated
- sheep(100294589) mucin 1, cell surface associated
- domestic guinea pig(100733534) mucin 1, cell surface associated
- naked mole-rat(101702421) mucin 1, cell surface associated
- Domestic Rabbit(100009240) mucin 1, cell surface associated
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MUC1 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-MUC1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8733, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species