MRPL22
mitochondrial ribosomal protein L22
Synonyms:
L22mt, MRP-L22, MRP-L25, RPML25
Species:
Human MRPL22 (29093), Mouse Mrpl22 (216767), Rat Mrpl22 (287302), sheep MRPL22 (101110505), domestic guinea pig Mrpl22 (100729278), naked mole-rat Mrpl22 (101714422), Zebrafish mrpl22 (100142645), fruit fly mRpL22 (32662), chicken MRPL22 (416253), domestic cat MRPL22 (101095716) ...More
UniProtKB ID:
Gene ID:
- Human(29093) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(216767) mitochondrial ribosomal protein L22
- Rat(287302) mitochondrial ribosomal protein L22
- sheep(101110505) mitochondrial ribosomal protein L22
- domestic guinea pig(100729278) mitochondrial ribosomal protein L22
- naked mole-rat(101714422) mitochondrial ribosomal protein L22
- Zebrafish(100142645) mitochondrial ribosomal protein L22
- fruit fly(32662) mitochondrial ribosomal protein L22
- chicken(416253) mitochondrial ribosomal protein L22
- domestic cat(101095716) mitochondrial ribosomal protein L22
- cow(614639) mitochondrial ribosomal protein L22
- dog(479320) mitochondrial ribosomal protein L22
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