MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
Synonyms:
MAPKAP-K2, MK-2, MK2
Species:
Human MAPKAPK2 (9261), Mouse Mapkapk2 (17164), Rat Mapkapk2 (289014), chicken MAPKAPK2 (419847), cow MAPKAPK2 (788091), dog MAPKAPK2 (490263), domestic cat MAPKAPK2 (101090833), naked mole-rat Mapkapk2 (101708612), Domestic Rabbit MAPKAPK2 (100009438), domestic guinea pig Mapkapk2 (100715906)
UniProtKB ID:
Gene ID:
- Human(9261) Summary: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(17164) MAP kinase-activated protein kinase 2
- Rat(289014) mitogen-activated protein kinase-activated protein kinase 2
- chicken(419847) mitogen-activated protein kinase-activated protein kinase 2
- cow(788091) mitogen-activated protein kinase-activated protein kinase 2
- dog(490263) mitogen-activated protein kinase-activated protein kinase 2
- domestic cat(101090833) mitogen-activated protein kinase-activated protein kinase 2
- naked mole-rat(101708612) mitogen-activated protein kinase-activated protein kinase 2
- Domestic Rabbit(100009438) mitogen-activated protein kinase-activated protein kinase 2
- domestic guinea pig(100715906) mitogen-activated protein kinase-activated protein kinase 2
- sheep(101118118) mitogen-activated protein kinase-activated protein kinase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MAPKAP-K2 Antibody, clone 7H4.2, clone 7H4.2, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-Phospho-MAPKAPK2-T334 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-MAPKAPK-2 Antibody, clone 1E16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, feline, horse, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-MAP Kinase 2/Erk2 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-MAP Kinase 2/Erk2 Antibody, clone 1B3B9, clone 1B3B9, Upstate®, from mouse,
Species Reactivity
avian, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
MAPKAPK2 human, recombinant, expressed in HEK 293 cells, ≥60 units/mg protein, buffered aqueous glycerol solution,
Species
human
MAPKAP Kinase Substrate Peptide, MAPKAP Kinase Substrate Peptide primarily used in Kinase Assays.,
Species
human