JAK3
Janus kinase 3
Synonyms:
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Species:
Human JAK3 (3718), Mouse Jak3 (16453), Rat Jak3 (25326), Zebrafish jak3 (561370), chicken JAK3 (395845), dog JAK3 (610004), cow JAK3 (538276), Horse JAK3 (100147451), domestic cat JAK3 (493680), domestic cat JAK3 (101092339) ...More
UniProtKB ID:
Gene ID:
- Human(3718) Summary: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
- Mouse(16453) Janus kinase 3
- Rat(25326) Janus kinase 3
- Zebrafish(561370) Janus kinase 3 (a protein tyrosine kinase, leukocyte)
- chicken(395845) Janus kinase 3
- dog(610004) Janus kinase 3
- cow(538276) Janus kinase 3
- Horse(100147451) Janus kinase 3
- domestic cat(493680) Janus kinase 3
- domestic cat(101092339) Janus kinase 3
- domestic guinea pig(100713900) Janus kinase 3
- naked mole-rat(101715472) Janus kinase 3
- sheep(101112816) Janus kinase 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-p-JAK3 (Tyr980/981) Antibody, clone 2D9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
canine, human, monkey, porcine
Application
affinity binding assay
flow cytometry
immunocytochemistry
western blot
flow cytometry
immunocytochemistry
western blot
Anti-JAK3 Antibody, serum, from rabbit,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-JAK3 Antibody, clone B32-32, clone B32-32, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
Jak3 Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
Species
human