ISCU
iron-sulfur cluster assembly enzyme
Synonyms:
2310020H20Rik, HML, ISU2, NIFU, NIFUN, hnifU
Species:
Human ISCU (23479), Mouse Iscu (66383), Rat Iscu (288740), chicken ISCU (416891), cow ISCU (514789), domestic cat ISCU (101088192), dog ISCU (477527), domestic guinea pig Iscu (100724516), naked mole-rat Iscu (101713201), sheep ISCU (101103093)
UniProtKB ID:
Gene ID:
- Human(23479) Summary: Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008]
- Mouse(66383) IscU iron-sulfur cluster scaffold homolog (E. coli)
- Rat(288740) iron-sulfur cluster scaffold homolog (E. coli)
- chicken(416891) iron-sulfur cluster scaffold homolog (E. coli)
- cow(514789) iron-sulfur cluster scaffold homolog (E. coli)
- domestic cat(101088192) iron-sulfur cluster scaffold homolog (E. coli)
- dog(477527) iron-sulfur cluster scaffold homolog (E. coli)
- domestic guinea pig(100724516) iron-sulfur cluster scaffold homolog (E. coli)
- naked mole-rat(101713201) iron-sulfur cluster scaffold homolog (E. coli)
- sheep(101103093) iron-sulfur cluster scaffold homolog (E. coli)
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