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Merck

IGF2R

insulin-like growth factor 2 receptor

Synonyms:
CD222, CIMPR, M6P-R, MPR1, MPRI
Species:
UniProtKB ID:
Gene ID:
  • Human(3482) Summary: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013]
  • Mouse(16004) insulin-like growth factor 2 receptor
  • Rat(25151) insulin-like growth factor 2 receptor
  • Goat(100860744) insulin-like growth factor 2 receptor
  • domestic guinea pig(100725901) insulin-like growth factor 2 receptor
  • naked mole-rat(101707470) insulin-like growth factor 2 receptor
  • Zebrafish(557061) insulin-like growth factor 2 receptor
  • domestic cat(100500935) insulin-like growth factor 2 receptor
  • Horse(100058539) insulin-like growth factor 2 receptor
  • cow(281849) insulin-like growth factor 2 receptor
  • dog(484067) insulin-like growth factor 2 receptor
  • chicken(395817) insulin-like growth factor 2 receptor

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IGF-2R/CD222 Antibody, clone 2O9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-MPR300/IGF-2R/CD222 Antibody, clone 2C2, clone 2C2, from mouse,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Cation-independent M6PR (IGF2R) Antibody, clone 4J4A3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IGF2R,
Species
human
MISSION® esiRNA, targeting mouse Igf2r,
Species
mouse