HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
Human HSD17B10 (3028), Mouse Hsd17b10 (15108), Rat Hsd17b10 (63864), Zebrafish hsd17b10 (450078), chicken HSD17B10 (425758), cow HSD17B10 (281809), domestic cat HSD17B10 (101090672), dog HSD17B10 (480930), domestic guinea pig Hsd17b10 (100718814), naked mole-rat Hsd17b10 (101712281)
- Human(3028) Summary: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
- Mouse(15108) hydroxysteroid (17-beta) dehydrogenase 10
- Rat(63864) hydroxysteroid (17-beta) dehydrogenase 10
- Zebrafish(450078) hydroxysteroid (17-beta) dehydrogenase 10
- chicken(425758) hydroxysteroid (17-beta) dehydrogenase 10
- cow(281809) hydroxysteroid (17-beta) dehydrogenase 10
- domestic cat(101090672) hydroxysteroid (17-beta) dehydrogenase 10
- dog(480930) hydroxysteroid (17-beta) dehydrogenase 10
- domestic guinea pig(100718814) hydroxysteroid (17-beta) dehydrogenase 10
- naked mole-rat(101712281) hydroxysteroid (17-beta) dehydrogenase 10
- sheep(101119880) hydroxysteroid (17-beta) dehydrogenase 10
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