HNF1B
HNF1 homeobox B
Synonyms:
FJHN, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1
Species:
Human HNF1B (6928), Mouse Hnf1b (21410), Rat Hnf1b (25640), chicken HNF1B (427838), cow HNF1B (503581), Horse HNF1B (100057769), domestic cat HNF1B (101081843), dog HNF1B (610402), domestic guinea pig Hnf1b (100734532), naked mole-rat Hnf1b (101711309)
UniProtKB ID:
Gene ID:
- Human(6928) Summary: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- Mouse(21410) HNF1 homeobox B
- Rat(25640) HNF1 homeobox B
- chicken(427838) HNF1 homeobox B
- cow(503581) HNF1 homeobox B
- Horse(100057769) HNF1 homeobox B
- domestic cat(101081843) HNF1 homeobox B
- dog(610402) HNF1 homeobox B
- domestic guinea pig(100734532) HNF1 homeobox B
- naked mole-rat(101711309) HNF1 homeobox B
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HNF-1-beta Antibody, clone 12A5.1, clone 12A5.1, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot