GLP2R
glucagon-like peptide 2 receptor
Synonyms:
Species:
Human GLP2R (9340), Mouse Glp2r (93896), Rat Glp2r (60432), sheep GLP2R (100174983), Domestic Rabbit GLP2R (100338519), domestic guinea pig Glp2r (100735903), naked mole-rat Glp2r (101725589), chicken GLP2R (427787), dog GLP2R (489499), domestic cat GLP2R (101083631) ...More
UniProtKB ID:
Gene ID:
- Human(9340) Summary: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008]
- Mouse(93896) glucagon-like peptide 2 receptor
- Rat(60432) glucagon-like peptide 2 receptor
- sheep(100174983) glucagon-like peptide 2 receptor
- Domestic Rabbit(100338519) glucagon-like peptide 2 receptor
- domestic guinea pig(100735903) glucagon-like peptide 2 receptor
- naked mole-rat(101725589) glucagon-like peptide 2 receptor
- chicken(427787) glucagon-like peptide 2 receptor
- dog(489499) glucagon-like peptide 2 receptor
- domestic cat(101083631) glucagon-like peptide 2 receptor
- cow(511942) glucagon-like peptide 2 receptor
- Horse(100073078) glucagon-like peptide 2 receptor
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