FGF4
fibroblast growth factor 4
Synonyms:
HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF
Species:
Human FGF4 (2249), Mouse Fgf4 (14175), Rat Fgf4 (116499), sheep FGF4 (101116004), naked mole-rat Fgf4 (101711919), domestic guinea pig Fgf4 (100730350), Zebrafish fgf4 (570435), cow FGF4 (618474), dog FGF4 (483680), chicken FGF4 (428857)
UniProtKB ID:
Gene ID:
- Human(2249) Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]
- Mouse(14175) fibroblast growth factor 4
- Rat(116499) fibroblast growth factor 4
- sheep(101116004) fibroblast growth factor 4
- naked mole-rat(101711919) fibroblast growth factor 4
- domestic guinea pig(100730350) fibroblast growth factor 4
- Zebrafish(570435) fibroblast growth factor 4
- cow(618474) fibroblast growth factor 4
- dog(483680) fibroblast growth factor 4
- chicken(428857) fibroblast growth factor 4
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