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Merck

EMR2

egf-like module containing, mucin-like, hormone receptor-like 2

Synonyms:
CD312
Species:
Human EMR2 (30817), cow EMR2 (787836), domestic cat EMR2 (101100284), dog EMR2 (610750), dog EMR2 (484898)
UniProtKB ID:
Q9UHX3, B4DQ96, E7ESD7, E9PBR1, E9PEL6, E9PFQ5, E9PG91, Q8NG96
Gene ID:
  • Human(30817) Summary: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
  • cow(787836) egf-like module containing, mucin-like, hormone receptor-like 2
  • domestic cat(101100284) egf-like module containing, mucin-like, hormone receptor-like 2
  • dog(610750) egf-like module containing, mucin-like, hormone receptor-like 2
  • dog(484898) egf-like module containing, mucin-like, hormone receptor-like 2

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