DNM2
dynamin 2
Synonyms:
CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Species:
Human DNM2 (1785), Mouse Dnm2 (13430), Rat Dnm2 (25751), dog DNM2 (484949), cow DNM2 (511691), domestic cat DNM2 (101100788), sheep DNM2 (101115027), domestic guinea pig Dnm2 (100717689), naked mole-rat Dnm2 (101696596)
UniProtKB ID:
Gene ID:
- Human(1785) Summary: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
- Mouse(13430) dynamin 2
- Rat(25751) dynamin 2
- dog(484949) dynamin 2
- cow(511691) dynamin 2
- domestic cat(101100788) dynamin 2
- sheep(101115027) dynamin 2
- domestic guinea pig(100717689) dynamin 2
- naked mole-rat(101696596) dynamin 2
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