DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
Synonyms:
AADC
Species:
Human DDC (1644), Mouse Ddc (13195), Rat Ddc (24311), domestic guinea pig Ddc (100135516), naked mole-rat Ddc (101697555), sheep DDC (101106765), Zebrafish ddc (406651), chicken DDC (420947), fruit fly Ddc (35190), dog DDC (606852) ...More
UniProtKB ID:
Gene ID:
- Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
- Mouse(13195) dopa decarboxylase
- Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- domestic guinea pig(100135516) dopa decarboxylase
- naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- Zebrafish(406651) dopa decarboxylase
- chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- fruit fly(35190) Dopa decarboxylase
- dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Dopa Decarboxylase Antibody, Chemicon®, from rabbit,
Species Reactivity
canine, human, sheep
Application
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Carbidopa for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
esiRNA
Product Number
Description
Species