CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Human CXCL1 (2919), Mouse Cxcl1 (14825), Rat Cxcl1 (81503), Horse CXCL1 (100034121), sheep CXCL1 (443380), domestic guinea pig Cxcl1 (100135510), naked mole-rat Cxcl1 (101705558)
- Human(2919) Summary: This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Jan 2012]
- Mouse(14825) chemokine (C-X-C motif) ligand 1
- Rat(81503) chemokine (C-X-C motif) ligand 1
- Horse(100034121) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
- sheep(443380) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
- domestic guinea pig(100135510) chemokine (C-X-C motif) ligand 1
- naked mole-rat(101705558) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
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