CTSK
cathepsin K
Synonyms:
CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD
Species:
Human CTSK (1513), Mouse Ctsk (13038), Rat Ctsk (29175), domestic guinea pig Ctsk (100718267), naked mole-rat Ctsk (101716993), sheep CTSK (101108972), Domestic Rabbit CTSK (100009334), Zebrafish ctsk (550475), chicken CTSK (395818), cow CTSK (513038) ...More
UniProtKB ID:
Gene ID:
- Human(1513) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
- Mouse(13038) cathepsin K
- Rat(29175) cathepsin K
- domestic guinea pig(100718267) cathepsin K
- naked mole-rat(101716993) cathepsin K
- sheep(101108972) cathepsin K
- Domestic Rabbit(100009334) cathepsin K
- Zebrafish(550475) cathepsin K
- chicken(395818) cathepsin K
- cow(513038) cathepsin K
- domestic cat(101093379) cathepsin K
- dog(608843) cathepsin K
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