CTLA4
cytotoxic T-lymphocyte-associated protein 4
Synonyms:
CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
Species:
Human CTLA4 (1493), Mouse Ctla4 (12477), Rat Ctla4 (63835), Domestic Rabbit CTLA4 (100009412), domestic guinea pig Ctla4 (100725760), naked mole-rat Ctla4 (101722788), chicken CTLA4 (424106), domestic cat CTLA4 (493743), cow CTLA4 (281732), dog CTLA4 (403696)
UniProtKB ID:
Gene ID:
- Human(1493) Summary: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
- Mouse(12477) cytotoxic T-lymphocyte-associated protein 4
- Rat(63835) cytotoxic T-lymphocyte-associated protein 4
- Domestic Rabbit(100009412) cytotoxic T-lymphocyte-associated protein 4
- domestic guinea pig(100725760) cytotoxic T-lymphocyte-associated protein 4
- naked mole-rat(101722788) cytotoxic T-lymphocyte-associated protein 4
- chicken(424106) cytotoxic T-lymphocyte-associated protein 4
- domestic cat(493743) cytotoxic T-lymphocyte-associated protein 4
- cow(281732) cytotoxic T-lymphocyte-associated protein 4
- dog(403696) cytotoxic T-lymphocyte-associated protein 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD152 (CTLA-4) Antibody (mouse), APC, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
Species Reactivity
mouse
Application
flow cytometry
Anti-CD152 (CTLA-4) Antibody (mouse), APC, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
Species Reactivity
mouse
Application
flow cytometry
Anti-CD152 (CTLA-4) (mouse), PE-Cy7, clone UC10-4F10-11 Antibody, clone UC10-4F10-11, from hamster(Armenian), PE-Cy7,
Species Reactivity
mouse
Application
flow cytometry
Anti-CD152 (CTLA-4) Antibody (mouse), PE, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
Species Reactivity
mouse
Application
flow cytometry
Anti-CTLA4/CD152 Antibody, clone 1D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species