CRTC2
CREB regulated transcription coactivator 2
Synonyms:
TORC-2, TORC2
Species:
Human CRTC2 (200186), Mouse Crtc2 (74343), Rat Crtc2 (310615), domestic guinea pig Crtc2 (100727423), naked mole-rat Crtc2 (101709168), sheep CRTC2 (101102117), cow CRTC2 (540959), Horse CRTC2 (100056571), domestic cat CRTC2 (101101104), dog CRTC2 (612305)
UniProtKB ID:
Gene ID:
- Human(200186) Summary: This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
- Mouse(74343) CREB regulated transcription coactivator 2
- Rat(310615) CREB regulated transcription coactivator 2
- domestic guinea pig(100727423) CREB regulated transcription coactivator 2
- naked mole-rat(101709168) CREB regulated transcription coactivator 2
- sheep(101102117) CREB regulated transcription coactivator 2
- cow(540959) CREB regulated transcription coactivator 2
- Horse(100056571) CREB regulated transcription coactivator 2
- domestic cat(101101104) CREB regulated transcription coactivator 2
- dog(612305) CREB regulated transcription coactivator 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CRTC2 Antibody, clone 5B10, ascites fluid, clone 5B10, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot