CNTFR
ciliary neurotrophic factor receptor
Synonyms:
Species:
Human CNTFR (1271), Mouse Cntfr (12804), Rat Cntfr (313173), sheep CNTFR (100294658), naked mole-rat Cntfr (101704145), domestic guinea pig Cntfr (100722634), Zebrafish cntfr (368438), dog CNTFR (442941), cow CNTFR (539548), Horse CNTFR (100146590) ...More
UniProtKB ID:
Gene ID:
- Human(1271) Summary: This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
- Mouse(12804) ciliary neurotrophic factor receptor
- Rat(313173) ciliary neurotrophic factor receptor
- sheep(100294658) ciliary neurotrophic factor receptor
- naked mole-rat(101704145) ciliary neurotrophic factor receptor
- domestic guinea pig(100722634) ciliary neurotrophic factor receptor
- Zebrafish(368438) ciliary neurotrophic factor receptor
- dog(442941) ciliary neurotrophic factor receptor
- cow(539548) ciliary neurotrophic factor receptor
- Horse(100146590) ciliary neurotrophic factor receptor
- domestic cat(101083719) ciliary neurotrophic factor receptor
- chicken(395885) ciliary neurotrophic factor receptor
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