CCNA1
cyclin A1
Synonyms:
Species:
Human CCNA1 (8900), Mouse Ccna1 (12427), Rat Ccna1 (295052), Zebrafish ccna1 (404206), cow CCNA1 (521939), domestic cat CCNA1 (101085426), chicken CCNA1 (418901), dog CCNA1 (477302), naked mole-rat Ccna1 (101718933), domestic guinea pig Ccna1 (100716489)
UniProtKB ID:
Gene ID:
- Human(8900) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12427) cyclin A1
- Rat(295052) cyclin A1
- Zebrafish(404206) cyclin A1
- cow(521939) cyclin A1
- domestic cat(101085426) cyclin A1
- chicken(418901) cyclin A1
- dog(477302) cyclin A1
- naked mole-rat(101718933) cyclin A1
- domestic guinea pig(100716489) cyclin A1
- sheep(101105579) cyclin A1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CCNA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry