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CASP8AP2

caspase 8 associated protein 2

Synonyms:

CED-4, FLASH, RIP25

Species:

Human CASP8AP2 (9994), Mouse Casp8ap2 (26885), Rat Casp8ap2 (313128), Zebrafish casp8ap2 (541521), cow CASP8AP2 (505138), Horse CASP8AP2 (100065766), domestic cat CASP8AP2 (101095416), dog CASP8AP2 (481921), chicken CASP8AP2 (421810), sheep CASP8AP2 (101109100) ...More

UniProtKB ID:

Q9UKL3, A2RUB7, E1P553, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9

Gene ID:

Human(9994) Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
Mouse(26885) caspase 8 associated protein 2
Rat(313128) caspase 8 associated protein 2
Zebrafish(541521) CASP8 associated protein 2
cow(505138) caspase 8 associated protein 2
Horse(100065766) caspase 8 associated protein 2
domestic cat(101095416) caspase 8 associated protein 2
dog(481921) caspase 8 associated protein 2
chicken(421810) caspase 8 associated protein 2
sheep(101109100) caspase 8 associated protein 2
Domestic Rabbit(100342805) caspase 8 associated protein 2
naked mole-rat(101700716) caspase 8 associated protein 2
domestic guinea pig(100729800) caspase 8 associated protein 2

Products (6)
Peer Reviewed Papers (18)

Custom & Knockdown Gene Products

siRNA
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Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

esiRNA

Product Number

Description

Species

MISSION^® esiRNA, targeting human CASP8AP2,

Species

human

MISSION^® esiRNA, targeting mouse Casp8ap2,

Species

mouse

Small Molecule - Substrate

Product Number

Description

Species

N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,

Species

rat, mouse, human

N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide, ≥95%,

Species

rat, mouse, human

N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,

Species

rat, mouse, human

N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,

Species

rat, mouse, human