BHMT2
betaine--homocysteine S-methyltransferase 2
Synonyms:
Species:
Human BHMT2 (23743), Mouse Bhmt2 (64918), Rat Bhmt2 (365972), naked mole-rat Bhmt2 (101720782), domestic guinea pig Bhmt2 (100718920), sheep BHMT2 (101108575), Horse BHMT2 (100073266), dog BHMT2 (488934), cow BHMT2 (616683), domestic cat BHMT2 (101084933)
UniProtKB ID:
Gene ID:
- Human(23743) Summary: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
- Mouse(64918) betaine-homocysteine methyltransferase 2
- Rat(365972) betaine-homocysteine S-methyltransferase 2
- naked mole-rat(101720782) betaine--homocysteine S-methyltransferase 2
- domestic guinea pig(100718920) betaine--homocysteine S-methyltransferase 2
- sheep(101108575) betaine--homocysteine S-methyltransferase 2
- Horse(100073266) betaine--homocysteine S-methyltransferase 2
- dog(488934) betaine--homocysteine S-methyltransferase 2
- cow(616683) betaine--homocysteine S-methyltransferase 2
- domestic cat(101084933) betaine--homocysteine S-methyltransferase 2
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