ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
Synonyms:
ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
Species:
Human ATP6V1B2 (526), Mouse Atp6v1b2 (11966), Rat Atp6v1b2 (117596), naked mole-rat Atp6v1b2 (101704199), domestic guinea pig Atp6v1b2 (100726524), sheep ATP6V1B2 (494439), Zebrafish atp6v1b2 (359840), cow ATP6V1B2 (338082), domestic cat ATP6V1B2 (101092601), dog ATP6V1B2 (486137)
UniProtKB ID:
Gene ID:
- Human(526) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
- Mouse(11966) ATPase, H+ transporting, lysosomal V1 subunit B2
- Rat(117596) ATPase, H transporting, lysosomal V1 subunit B2
- naked mole-rat(101704199) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
- domestic guinea pig(100726524) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
- sheep(494439) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
- Zebrafish(359840) ATPase, H+ transporting, lysosomal V1 subunit B2
- cow(338082) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
- domestic cat(101092601) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
- dog(486137) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
- chicken(395497) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
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