ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Synonyms:
ATP2B, DAR, DD, SERCA2
Species:
Human ATP2A2 (488), Mouse Atp2a2 (11938), Rat Atp2a2 (29693), chicken ATP2A2 (396446), domestic cat ATP2A2 (493691), cow ATP2A2 (540568), Horse ATP2A2 (791242), dog ATP2A2 (403878), naked mole-rat Atp2a2 (101720630), domestic guinea pig Atp2a2 (100174978) ...More
UniProtKB ID:
Gene ID:
- Human(488) Summary: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]
- Mouse(11938) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- Rat(29693) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- chicken(396446) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- domestic cat(493691) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- cow(540568) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- Horse(791242) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- dog(403878) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- naked mole-rat(101720630) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- domestic guinea pig(100174978) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- sheep(101104344) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- Domestic Rabbit(100038308) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- sheep(100526801) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ATP2A2/SERCA2 Antibody, clone 1G13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SERCA2 Antibody, clone IID8, clone IID8, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SERCA2/ATP2A2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot