ADRA2C

adrenoceptor alpha 2C

Synonyms:

ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR

Species:

UniProtKB ID:

Gene ID:

Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
Mouse(11553) adrenergic receptor, alpha 2c
Rat(24175) adrenoceptor alpha 2C
domestic guinea pig(100135477) adrenergic receptor, alpha 2c
domestic guinea pig(101787589) adrenoceptor alpha 2C
sheep(100170319) adrenoceptor alpha 2C
Zebrafish(266752) adrenergic, alpha-2C-, receptor
cow(407139) alpha-2C adrenergic receptor
cow(101902575) adrenoceptor alpha 2C
chicken(428799) adrenergic, alpha-2C-, receptor
dog(488793) adrenoceptor alpha 2C
domestic cat(100529244) adrenoceptor alpha 2C
domestic cat(101087990) adrenoceptor alpha 2C

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