ADRA1B

adrenoceptor alpha 1B

Synonyms:

ADRA1, ALPHA1BAR

Species:

UniProtKB ID:

Gene ID:

Human(147) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
Mouse(11548) adrenergic receptor, alpha 1b
Rat(24173) adrenoceptor alpha 1B
chicken(373890) adrenergic, alpha-1B-, receptor
domestic cat(101092238) adrenoceptor alpha 1B
cow(407140) adrenergic, alpha-1B-, receptor
dog(403962) adrenoceptor alpha 1B
domestic guinea pig(100735480) adrenoceptor alpha 1B
sheep(101114869) adrenoceptor alpha 1B
Domestic Rabbit(100008731) adrenoceptor alpha 1B

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