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Merck

Transform your microscope

CellASIC® ONIX2 Live Cell Imaging System


The ability to grow, observe and manipulate complex cell cultures requires precision control over the cell culture environment. The CellASIC® ONIX2 Microfluidic System transforms your existing microscope into an automated system for advanced live-cell imaging and analysis.

  • Dynamic live cell imaging
  • Compatible with any inverted microscope
  • Small footprint
  • User-friendly operation
  • Optically clear microfluidic plates for many applications
  • Integrated microincubator controller maintains culture environment
CellASIC® ONIX2 microfluidics – how it works in live cell imaging

How it works

The CellASIC® ONIX2 system creates a vacuum seal with specialized microfluidic plates and controls perfusion, temperature, and gas environment. Adherent or suspension cells are added directly to the four cell inlet wells of the microfluidic plate. Capillary-driven cell loading automatically loads cells into the culture chambers in a gentle, well-distributed manner. Media or reagents are loaded into the solution inlet wells. Individual microchannels connect each solution to the cell culture chambers in the imaging area of the microfluidic plate. The manifold connecting the plates to the system can be adapted to any inverted microscope.


Life is dynamic

Explore our tech articles and protocols for live cell imaging using the CellASIC® ONIX2 system.


Products
Product No.Product NameDescriptionPricing
CAX2-S0000CellASIC ONIX2 Microfluidic System
B04A-03CellASIC ONIX plate for bacteria cells (4 chamber)The B04 plates utilize a microfabricated silicone ceiling with a height similar to bacteria cells to restrict their growth in a single focal plane & maintain x,y position over time.
Y04C-02-5PKCellASIC ONIX plate for haploid yeast cells (4 chamber, 3.5-5 micron)The Y04 plates for Haploid Yeast Cells utilize a microfabricated silicone ceiling with a height similar to yeast cells to restrict their growth in a single focal plane & maintaining x,y position over time.
CAX2-MBC20CellASIC ONIX2 Manifold Basic (No Temperature Control)The CellASIC ONIX2 Manifold Basic seals to the CellASIC ONIX plates and delivers a defined gas environment to the cell culture region.
M04S-03-5PKCellASIC ONIX switching plate mammalian cells (4 chamber)The M04 switching plates enable continuous perfusion culture for live cell analysis. Laminar flow provides rapid & uniform solution exchange for maximum cell health. The glass coverslide bottom surface ensures the highest resolution optical viewing.
M04G-02-5PKCellASIC ONIX gradient plate for mammalian cells (4 chamber)The M04 gradient plates enable continuous perfusion culture for live cell analysis. Laminar flow provides rapid & uniform solution exchange for maximum cell health. The glass coverslide bottom surface ensures the highest resolution optical viewing.
CAX2-MXT20CellASIC ONIX2 Manifold XT (Temperature Controlled)
M04L-03-5PKCellASIC ONIX open-top plate for mammalian cells (4 chamber)The M04 open top plates enable continuous perfusion culture for live cell analysis. Laminar flow provides rapid & uniform solution exchange for maximum cell health. The glass coverslide bottom surface ensures the highest resolution optical viewing.
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